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Case Study: Continuous Glucose Monitoring
Business Challenge:
An established company that is developing a continuous glucose monitoring solution approached BEST-Bio for consulting services. At certain glucose levels, they were observing spurious results from their meter in the form of noisy data and eventual loss of signal. BEST-Bio was to determine the source of the noise and provide suggestions for solving the issue.
BEST-Bio Solution:
BEST-Bio recognizes that the signal from a continuous glucose monitor is dependent on three primary factors:
  • The bioelectrochemical sensor - including enzyme kinetics, mass transfer, etc.
  • The connections to the meter - including conducting tracks on the sensor and electrical connectors
  • The electronics in the meter
  • BEST-Bio used its problem solving skills to determine that the problem resided in the meter electronics. By testing the electronics with calibrated resistors, we were able to determine that the electronics were unable to handle the currents expected in the offending glucose concentration ranges.
    BEST-Bio's team of electronics experts were able to provide a solution to allow the meter to handle the full range of glucose concentrations, eliminating the noise and loss of signal that had been observed by the client.
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